Dimethyl fumarate impairs differentiated B cells and fosters central nervous system integrity in treatment of multiple sclerosis

In multiple sclerosis (MS), the effect of dimethyl fumarate (DMF) treatment is primarily attributed to its capacity to dampen pathogenic T cells. Here, we tested whether DMF also modulates B cells, which are newly recognized key players in MS, and to which extent DMF restricts ongoing loss of oligod...

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Библиографические подробности
Опубликовано в: :Brain Pathol
Главные авторы: Traub, Jan, Traffehn, Sarah, Ochs, Jasmin, Häusser‐Kinzel, Silke, Stephan, Schirin, Scannevin, Robert, Brück, Wolfgang, Metz, Imke, Weber, Martin S.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849574/
https://ncbi.nlm.nih.gov/pubmed/30706542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12711
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