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EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA

Oncogene amplification is one of the most common drivers of genetic events in cancer, potently promoting tumor development, growth, and progression. The recent discovery that oncogene amplification commonly occurs on extrachromosomal DNA, driving intratumoral genetic heterogeneity and high copy numb...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Rajkumar, Utkrisht, Turner, Kristen, Luebeck, Jens, Deshpande, Viraj, Chandraker, Manmohan, Mischel, Paul, Bafna, Vineet
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849072/
https://ncbi.nlm.nih.gov/pubmed/31706138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.10.035
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