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Reliable variant calling during runtime of Illumina sequencing

The sequential paradigm of data acquisition and analysis in next-generation sequencing leads to high turnaround times for the generation of interpretable results. We combined a novel real-time read mapping algorithm with fast variant calling to obtain reliable variant calls still during the sequenci...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Loka, Tobias P., Tausch, Simon H., Renard, Bernhard Y.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848508/
https://ncbi.nlm.nih.gov/pubmed/31712740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52991-z
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