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Large Scale Loss of Data in Low-Diversity Illumina Sequencing Libraries Can Be Recovered by Deferred Cluster Calling

Massively parallel DNA sequencing is capable of sequencing tens of millions of DNA fragments at the same time. However, sequence bias in the initial cycles, which are used to determine the coordinates of individual clusters, causes a loss of fidelity in cluster identification on Illumina Genome Anal...

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Detalhes bibliográficos
Main Authors: Krueger, Felix, Andrews, Simon R., Osborne, Cameron S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030592/
https://ncbi.nlm.nih.gov/pubmed/21305042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016607
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