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Impact of Three Illumina Library Construction Methods on GC Bias and HLA Genotype Calling
Next-generation sequencing (NGS) is increasingly recognized for its ability to overcome allele ambiguity and deliver high-resolution typing in the human leukocyte antigen (HLA) system. Using this technology, non-uniform read distribution can impede the reliability of variant detection, which renders...
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| Publicado no: | Hum Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089167/ https://ncbi.nlm.nih.gov/pubmed/25543015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2014.12.016 |
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