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An adaptive decorrelation method removes Illumina DNA base-calling errors caused by crosstalk between adjacent clusters

Base-calling accuracy is crucial for high-throughput DNA sequencing and downstream analysis such as read mapping and genome assembly. Accordingly, we made an endeavor to reduce DNA sequencing errors of Illumina systems by correcting three kinds of crosstalk in the cluster intensity data. We discover...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Bo, Wan, Lin, Wang, Anqi, Li, Lei M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316982/
https://ncbi.nlm.nih.gov/pubmed/28216647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41348
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