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An adaptive decorrelation method removes Illumina DNA base-calling errors caused by crosstalk between adjacent clusters

Base-calling accuracy is crucial for high-throughput DNA sequencing and downstream analysis such as read mapping and genome assembly. Accordingly, we made an endeavor to reduce DNA sequencing errors of Illumina systems by correcting three kinds of crosstalk in the cluster intensity data. We discover...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Wang, Bo, Wan, Lin, Wang, Anqi, Li, Lei M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316982/
https://ncbi.nlm.nih.gov/pubmed/28216647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41348
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