NIMG-09. NONINVASIVE PERFUSION IMAGING BIOMARKER OF MALIGNANT GENOTYPE IN ISOCITRATE DEHYDROGENASE MUTANT GLIOMAS

OBJECTIVE: A small subset of IDHmut astrocytomas behave aggressively, similarly to IDHwt glioblastoma. Genomic correlates of poor prognosis IDHmut astrocytomas include global relative DNA hypomethylation, MYCN amplification copy number variation (CNV) abundance, and CDKN2A/B homozygous deletion. We...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Mureb, Monica, Jain, Rajan, Poisson, Laila, Aguiar Littig, Ingrid, Nunes Neto, Lucidio, Wu, Chih-Chin, Ng, Victor, Patel, Sohil, Patel, Seema, Serrano, Jonathan, Kurz, Sylvia, Cahill, Daniel, Bendszus, Martin, von Deimling, Andreas, Placantonakis, Dimitris, Golfinos, John, Kickingereder, Philipp, Snuderl, Matija, Chi, Andrew
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Neuro-Imaging
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847952/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.681
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