NIMG-09. NONINVASIVE PERFUSION IMAGING BIOMARKER OF MALIGNANT GENOTYPE IN ISOCITRATE DEHYDROGENASE MUTANT GLIOMAS

OBJECTIVE: A small subset of IDHmut astrocytomas behave aggressively, similarly to IDHwt glioblastoma. Genomic correlates of poor prognosis IDHmut astrocytomas include global relative DNA hypomethylation, MYCN amplification copy number variation (CNV) abundance, and CDKN2A/B homozygous deletion. We...

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Vydáno v:Neuro Oncol
Hlavní autoři: Mureb, Monica, Jain, Rajan, Poisson, Laila, Aguiar Littig, Ingrid, Nunes Neto, Lucidio, Wu, Chih-Chin, Ng, Victor, Patel, Sohil, Patel, Seema, Serrano, Jonathan, Kurz, Sylvia, Cahill, Daniel, Bendszus, Martin, von Deimling, Andreas, Placantonakis, Dimitris, Golfinos, John, Kickingereder, Philipp, Snuderl, Matija, Chi, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Neuro-Imaging
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847952/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.681
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