NIMG-09. NONINVASIVE PERFUSION IMAGING BIOMARKER OF MALIGNANT GENOTYPE IN ISOCITRATE DEHYDROGENASE MUTANT GLIOMAS

OBJECTIVE: A small subset of IDHmut astrocytomas behave aggressively, similarly to IDHwt glioblastoma. Genomic correlates of poor prognosis IDHmut astrocytomas include global relative DNA hypomethylation, MYCN amplification copy number variation (CNV) abundance, and CDKN2A/B homozygous deletion. We...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Mureb, Monica, Jain, Rajan, Poisson, Laila, Aguiar Littig, Ingrid, Nunes Neto, Lucidio, Wu, Chih-Chin, Ng, Victor, Patel, Sohil, Patel, Seema, Serrano, Jonathan, Kurz, Sylvia, Cahill, Daniel, Bendszus, Martin, von Deimling, Andreas, Placantonakis, Dimitris, Golfinos, John, Kickingereder, Philipp, Snuderl, Matija, Chi, Andrew
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Neuro-Imaging
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847952/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.681
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