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EXTH-70. ENHANCEMENT OF ANTITUMOR ACTIVITY BY USING 5-ALA–MEDIATED SONODYNAMIC THERAPY TO INDUCE APOPTOSIS AND NECROSIS IN A MOUSE GLIOMA MODEL

OBJECTIVE: High invasiveness of malignant gliomas frequently causes local tumor recurrence. To control such recurrence, novel therapies targeted toward infiltrating glioma cells are required. Here, we examined cytotoxic effects of sonodynamic therapy (SDT) combined with a sonosensitizer, 5-aminolevu...

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Publicado en:Neuro Oncol
Main Authors: Suehiro, Satoshi, Ohnishi, Takanori, Inoue, Akihiro, Yamashita, Daisuke, Nishikawa, Masahiro, Ohue, Shiro, Kunieda, Takeharu
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847572/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.400
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