EXTH-70. ENHANCEMENT OF ANTITUMOR ACTIVITY BY USING 5-ALA–MEDIATED SONODYNAMIC THERAPY TO INDUCE APOPTOSIS AND NECROSIS IN A MOUSE GLIOMA MODEL

OBJECTIVE: High invasiveness of malignant gliomas frequently causes local tumor recurrence. To control such recurrence, novel therapies targeted toward infiltrating glioma cells are required. Here, we examined cytotoxic effects of sonodynamic therapy (SDT) combined with a sonosensitizer, 5-aminolevu...

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Udgivet i:Neuro Oncol
Main Authors: Suehiro, Satoshi, Ohnishi, Takanori, Inoue, Akihiro, Yamashita, Daisuke, Nishikawa, Masahiro, Ohue, Shiro, Kunieda, Takeharu
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847572/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.400
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