EXTH-70. ENHANCEMENT OF ANTITUMOR ACTIVITY BY USING 5-ALA–MEDIATED SONODYNAMIC THERAPY TO INDUCE APOPTOSIS AND NECROSIS IN A MOUSE GLIOMA MODEL

OBJECTIVE: High invasiveness of malignant gliomas frequently causes local tumor recurrence. To control such recurrence, novel therapies targeted toward infiltrating glioma cells are required. Here, we examined cytotoxic effects of sonodynamic therapy (SDT) combined with a sonosensitizer, 5-aminolevu...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Suehiro, Satoshi, Ohnishi, Takanori, Inoue, Akihiro, Yamashita, Daisuke, Nishikawa, Masahiro, Ohue, Shiro, Kunieda, Takeharu
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847572/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.400
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