EXTH-70. ENHANCEMENT OF ANTITUMOR ACTIVITY BY USING 5-ALA–MEDIATED SONODYNAMIC THERAPY TO INDUCE APOPTOSIS AND NECROSIS IN A MOUSE GLIOMA MODEL

OBJECTIVE: High invasiveness of malignant gliomas frequently causes local tumor recurrence. To control such recurrence, novel therapies targeted toward infiltrating glioma cells are required. Here, we examined cytotoxic effects of sonodynamic therapy (SDT) combined with a sonosensitizer, 5-aminolevu...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Suehiro, Satoshi, Ohnishi, Takanori, Inoue, Akihiro, Yamashita, Daisuke, Nishikawa, Masahiro, Ohue, Shiro, Kunieda, Takeharu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847572/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.400
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