EXTH-70. ENHANCEMENT OF ANTITUMOR ACTIVITY BY USING 5-ALA–MEDIATED SONODYNAMIC THERAPY TO INDUCE APOPTOSIS AND NECROSIS IN A MOUSE GLIOMA MODEL

OBJECTIVE: High invasiveness of malignant gliomas frequently causes local tumor recurrence. To control such recurrence, novel therapies targeted toward infiltrating glioma cells are required. Here, we examined cytotoxic effects of sonodynamic therapy (SDT) combined with a sonosensitizer, 5-aminolevu...

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Publicat a:Neuro Oncol
Autors principals: Suehiro, Satoshi, Ohnishi, Takanori, Inoue, Akihiro, Yamashita, Daisuke, Nishikawa, Masahiro, Ohue, Shiro, Kunieda, Takeharu
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847572/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.400
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