DRES-08. CLINICAL SIGNIFICANCE OF HYPERMUTATION IN GLIOMAS

BACKGROUND: Hypermutation is an emerging biomarker for predicting response to immunotherapy in cancer patients, however its clinical value in gliomas is not established. We sought to assess the determinants of hypermutation in gliomas, and its value for predicting response to standard of care and im...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Touat, Mehdi, Li, Yvonne, Boynton, Adam, Spurr, Liam, Iorgulescu, Bryan, Birzu, Christina, Pal, Sangita, Ferrer-Luna, Ruben, Geduldig, Jack, Bellamy, Charlotte, Younan, Nadia, Baldini, Capucine, Verreault, Maite, Guillerm, Erell, Ammari, Samy, Beuvon, Frederic, Mokhtari, Karima, Alentorn, Agusti, Dehais, Caroline, Houiller, Caroline, Laigle-Donadey, Florence, Lee, Eudocia, Nayak, Lakshmi, Carpentier, Alexandre, Cornu, Philippe, mathon, Bertrand, Bi, Wenya, Chiocca, Ennio, Alexandrescu, Sanda, Chi, Susan, Haas-Kogan, Daphne, Alexander, Brian, Huang, Raymond, Ligon, Azra, Coulet, Florence, Delattre, Jean-Yves, Hoang-Xuan, Khe, Meredith, David, Santagata, Sandro, Duval, Alex, Sanson, Marc, Cherniack, Andrew, Wen, Patrick, Reardon, David, Marabelle, Aurelien, Idbaih, Ahmed, Beroukhim, Rameen, Bandopadhayay, Pratiti, Bielle, Franck, Ligon, Keith
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Drug Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847135/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.296
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