DRES-08. CLINICAL SIGNIFICANCE OF HYPERMUTATION IN GLIOMAS

BACKGROUND: Hypermutation is an emerging biomarker for predicting response to immunotherapy in cancer patients, however its clinical value in gliomas is not established. We sought to assess the determinants of hypermutation in gliomas, and its value for predicting response to standard of care and im...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Touat, Mehdi, Li, Yvonne, Boynton, Adam, Spurr, Liam, Iorgulescu, Bryan, Birzu, Christina, Pal, Sangita, Ferrer-Luna, Ruben, Geduldig, Jack, Bellamy, Charlotte, Younan, Nadia, Baldini, Capucine, Verreault, Maite, Guillerm, Erell, Ammari, Samy, Beuvon, Frederic, Mokhtari, Karima, Alentorn, Agusti, Dehais, Caroline, Houiller, Caroline, Laigle-Donadey, Florence, Lee, Eudocia, Nayak, Lakshmi, Carpentier, Alexandre, Cornu, Philippe, mathon, Bertrand, Bi, Wenya, Chiocca, Ennio, Alexandrescu, Sanda, Chi, Susan, Haas-Kogan, Daphne, Alexander, Brian, Huang, Raymond, Ligon, Azra, Coulet, Florence, Delattre, Jean-Yves, Hoang-Xuan, Khe, Meredith, David, Santagata, Sandro, Duval, Alex, Sanson, Marc, Cherniack, Andrew, Wen, Patrick, Reardon, David, Marabelle, Aurelien, Idbaih, Ahmed, Beroukhim, Rameen, Bandopadhayay, Pratiti, Bielle, Franck, Ligon, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Drug Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847135/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.296
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