PATH-16. MOLECULAR PATHOLOGY AND CLINICAL CHARACTERISTICS OF MMR DEFICIENCY (MMRd) IN DIFFUSE GLIOMAS

BACKGROUND: MMR deficiency (MMRd) is found in a subset of gliomas. Emerging evidence indicates that MMRd could serve as predictive biomarker for both response to immunotherapy and resistance to alkylating agents. However, the molecular epidemiology, outcome, and the optimal diagnostic method of MMRd...

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Publicado no:Neuro Oncol
Main Authors: Touat, Mehdi, Santagata, Sandro, Guillerm, Erell, Bi, Wenya, Beuvon, Frédéric, Mokhtari, Karima, Giry, Marine, Guegan, Justine, Block, Shannon, Carpentier, Alexandre, Delattre, Jean-Yves, Sanson, Marc, Duval, Alex, Beroukhim, Rameen, Bandopadhayay, Pratiti, Reardon, David, Wen, Patrick, Idbaih, Ahmed, Coulet, Florence, Ligon, Keith, Bielle, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216513/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.672
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