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Prevalence, clinico-pathological value, and co-occurrence of PDGFRA abnormalities in diffuse gliomas

PDGFRA is a critical gene in glioma biology. Similar to EGFR, PDGFRA has been shown to be overexpressed, amplified, mutated, or truncated in gliomas, particularly glioblastomas. In addition, PDGFRA has been recently shown to be rearranged in glioblastoma. However, the frequency, cooccurrence, and cl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alentorn, Agustí, Marie, Yannick, Carpentier, Catherine, Boisselier, Blandine, Giry, Marine, Labussière, Marianne, Mokhtari, Karima, Hoang-Xuan, Khê, Sanson, Marc, Delattre, Jean-Yves, Idbaih, Ahmed
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480267/
https://ncbi.nlm.nih.gov/pubmed/23074200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos217
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