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Chromosome 9p and 10q losses predict unfavorable outcome in low-grade gliomas

The loss of chromosomes 1p–19q is the only prognostic molecular alteration identified in low-grade gliomas (LGGs) to date. Search for loss of heterozygosity (LOH) on chromosomes 1p, 9p, 10q, and 19q was performed in a series of 231 LGGs. Loss of chromosomes 1p–19q was strongly correlated with prolon...

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Detalhes bibliográficos
Main Authors: Houillier, Caroline, Mokhtari, Karima, Carpentier, Catherine, Crinière, Emmanuelle, Marie, Yannick, Rousseau, Audrey, Kaloshi, Gentian, Dehais, Caroline, Laffaire, Julien, Laigle-Donadey, Florence, Hoang-Xuan, Khê, Sanson, Marc, Delattre, Jean-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940555/
https://ncbi.nlm.nih.gov/pubmed/20150361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop002
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