DRES-13. DUAL KINASE INHIBITION TO COMBAT EGFR-INHIBITOR RESISTANCE IN GLIOBLASTOMA

Glioblastoma (GBM) is an aggressive primary brain tumor with a poor survival rate. One of the most common molecular alterations seen in GBM is amplification and/or mutation of the Epidermal Growth Factor Receptor (EGFR), which has made it an attractive therapeutic target. However, several EGFR tyros...

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Vydáno v:Neuro Oncol
Hlavní autoři: Smithberger, Erin, Shelton, Abigail, Butler, Madison, Flores, Alex, Bash, Ryan, Angus, Steven, East, Michael, Sciaky, Noah, Dhruv, Harshil, Johnson, Gary, Berens, Michael, Furnari, Frank, Ryan Miller, C
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Drug Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846925/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.300
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