TMOD-36. DEVELOPMENT OF A PATIENT-DERIVED ORTHOTOPIC XENOGRAFT GLIOBLASTOMA MODEL PHENOTYPICALLY REPRESENTATIVE OF THE CLINICAL FEATURES

In murine models, patient derived orthotopic xenografts (PDOXs) generated from neurosphere cultures of human glioblastomas (GBMs) are unmatched in representing the molecular heterogeneity of the disease. However, intra-axial tumors with blood-brain barrier (BBB) breakdown visible on magnetic resonan...

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發表在:Neuro Oncol
Main Authors: Nagaraja, Tavarekere, deCarvalho, Ana, Griffith, Brent, Brown, Stephen, Divine, George, Irtenkauf, Susan, Knight, Robert, Lee, Ian, Panda, Swayamprava, Cabral, Glauber, Ewing, James
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
Tumor Models
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846599/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1135
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