TMOD-36. DEVELOPMENT OF A PATIENT-DERIVED ORTHOTOPIC XENOGRAFT GLIOBLASTOMA MODEL PHENOTYPICALLY REPRESENTATIVE OF THE CLINICAL FEATURES

In murine models, patient derived orthotopic xenografts (PDOXs) generated from neurosphere cultures of human glioblastomas (GBMs) are unmatched in representing the molecular heterogeneity of the disease. However, intra-axial tumors with blood-brain barrier (BBB) breakdown visible on magnetic resonan...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Nagaraja, Tavarekere, deCarvalho, Ana, Griffith, Brent, Brown, Stephen, Divine, George, Irtenkauf, Susan, Knight, Robert, Lee, Ian, Panda, Swayamprava, Cabral, Glauber, Ewing, James
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Tumor Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846599/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1135
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