TMOD-36. DEVELOPMENT OF A PATIENT-DERIVED ORTHOTOPIC XENOGRAFT GLIOBLASTOMA MODEL PHENOTYPICALLY REPRESENTATIVE OF THE CLINICAL FEATURES

In murine models, patient derived orthotopic xenografts (PDOXs) generated from neurosphere cultures of human glioblastomas (GBMs) are unmatched in representing the molecular heterogeneity of the disease. However, intra-axial tumors with blood-brain barrier (BBB) breakdown visible on magnetic resonan...

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Sparad:
Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Nagaraja, Tavarekere, deCarvalho, Ana, Griffith, Brent, Brown, Stephen, Divine, George, Irtenkauf, Susan, Knight, Robert, Lee, Ian, Panda, Swayamprava, Cabral, Glauber, Ewing, James
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Tumor Models
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846599/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1135
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