SCIDOT-14. ENHANCING BRAIN RETENTION OF A KIF11 INHIBITOR SIGNIFICANTLY IMPROVES ITS EFFICACY IN A MOUSE MODEL OF GLIOBLASTOMA

Glioblastoma, the most common and lethal of brain tumors, is both highly invasive and proliferative. This allows tumor cells to infiltrate into regions of the brain with an intact blood brain barrier and be protected from effective therapeutics. Thus, an ideal glioblastoma therapy needs to target ce...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Gampa, Gautham, Kenchappa, Rajappa, Mohammad, Afroz, Parrish, Karen, Kim, Minjee, Sarkaria, Jann, Rosenfeld, Steven, Elmquist, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Abstracts from the 3rd Sno-Scidot Joint Conference on Therapeutic Delivery to the CNS
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845720/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1150
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