SCIDOT-19. A MECHANICALLY-ENGINEERED SPRAY TO INCREASE BRAIN PENETRATION OF CHEMOTHERAPEUTIC NANOPARTICLES IN THE TREATMENT OF HIGH-GRADE GLIOMAS

Design and implementation of innovative local drug delivery systems (DDS) may overcome current limitations in GBM treatment, such as the lack of therapeutic drug concentrations reaching residual GBM cells following surgery. Here we describe a novel DDS which utilises a bespoke mechanically engineere...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: McCrorie, Phoebe, Taresco, Vincenzo, Xu, Zeyuan, Ritchie, Alison, A Clarke, Philip, Marlow, Maria, Rahman, Ruman
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Abstracts from the 3rd Sno-Scidot Joint Conference on Therapeutic Delivery to the CNS
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845641/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1155
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