SCIDOT-19. A MECHANICALLY-ENGINEERED SPRAY TO INCREASE BRAIN PENETRATION OF CHEMOTHERAPEUTIC NANOPARTICLES IN THE TREATMENT OF HIGH-GRADE GLIOMAS

Design and implementation of innovative local drug delivery systems (DDS) may overcome current limitations in GBM treatment, such as the lack of therapeutic drug concentrations reaching residual GBM cells following surgery. Here we describe a novel DDS which utilises a bespoke mechanically engineere...

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Pubblicato in:Neuro Oncol
Autori principali: McCrorie, Phoebe, Taresco, Vincenzo, Xu, Zeyuan, Ritchie, Alison, A Clarke, Philip, Marlow, Maria, Rahman, Ruman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Abstracts from the 3rd Sno-Scidot Joint Conference on Therapeutic Delivery to the CNS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845641/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1155
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