Pharmacokinetics and Metabolite Profiling of Trepibutone in Rats Using Ultra-High Performance Liquid Chromatography Combined With Hybrid Quadrupole-Orbitrap and Triple Quadrupole Mass Spectrometers

Trepibutone was widely used for cholelithiasis, cholecystitis, biliary tract dyskinesia, cholecystectomy syndrome, and chronic pancreatitis in clinic. However, few investigations on trepibutone have been conducted. In this study, an accurate, sensitive, and selective analytical method was developed...

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Detaylı Bibliyografya
Yayımlandı:Front Pharmacol
Asıl Yazarlar: Sun, Zhi, Yang, Jie, Liu, Liwei, Xu, Yanyan, Zhou, Lin, Jia, Qingquan, Shi, Yingying, Du, Xiangyu, Kang, Jian, Zuo, Lihua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843799/
https://ncbi.nlm.nih.gov/pubmed/31749700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01266
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