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Renal secretion of hydrochlorothiazide involves organic anion transporter 1/3, organic cation transporter 2, and multidrug and toxin extrusion protein 2-K

Hydrochlorothiazide (HCTZ) is the most widely used thiazide diuretic for the treatment of hypertension either alone or in combination with other antihypertensives. HCTZ is mainly cleared by the kidney via tubular secretion, but the underlying molecular mechanisms are unclear. Using cells stably expr...

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Bibliografski detalji
Izdano u:Am J Physiol Renal Physiol
Glavni autori: Yin, Jia, Wagner, David J., Prasad, Bhagwat, Isoherranen, Nina, Thummel, Kenneth E., Wang, Joanne
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843032/
https://ncbi.nlm.nih.gov/pubmed/31322418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00141.2019
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