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Interaction and Transport of Methamphetamine and its Primary Metabolites by Organic Cation and Multidrug and Toxin Extrusion Transporters

Methamphetamine is one of the most abused illicit drugs with roughly 1.2 million users in the United States alone. A large portion of methamphetamine and its metabolites is eliminated by the kidney with renal clearance larger than glomerular filtration clearance. Yet the mechanism of active renal se...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Principais autores: Wagner, David J., Sager, Jennifer E., Duan, Haichuan, Isoherranen, Nina, Wang, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478906/
https://ncbi.nlm.nih.gov/pubmed/28428365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.074708
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