MMP3 activity rather than cortical stiffness determines NHE1-dependent invasiveness of melanoma cells

BACKGROUND: Both cell adhesion and matrix metalloproteinase (MMP) activity depend on pH at the cell surface. By regulating extracellular juxtamembrane pH, the Na(+)/H(+) exchanger NHE1 plays a significant part in human melanoma (MV3) cell migration and invasion. Because NHE1, besides its pH-regulato...

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Detaylı Bibliyografya
Yayımlandı:Cancer Cell Int
Asıl Yazarlar: Keurhorst, Dennis, Liashkovich, Ivan, Frontzek, Fabian, Nitzlaff, Svenja, Hofschröer, Verena, Dreier, Rita, Stock, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Primary Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842528/
https://ncbi.nlm.nih.gov/pubmed/31728131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1015-7
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