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Cell mechanosensing is regulated by substrate strain energy rather than stiffness

The ability of cells to perceive the mechanical identity of extracellular matrix, generally known as mechanosensing, is generally depicted as a consequence of an intricate balance between pulling forces actuated by the actin fibers on the adhesion plaques and the mechanical reaction of the supportin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Panzetta, Valeria, Fusco, Sabato, Netti, Paolo A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825315/
https://ncbi.nlm.nih.gov/pubmed/31570575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904660116
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