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Cell mechanosensing is regulated by substrate strain energy rather than stiffness

The ability of cells to perceive the mechanical identity of extracellular matrix, generally known as mechanosensing, is generally depicted as a consequence of an intricate balance between pulling forces actuated by the actin fibers on the adhesion plaques and the mechanical reaction of the supportin...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Panzetta, Valeria, Fusco, Sabato, Netti, Paolo A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825315/
https://ncbi.nlm.nih.gov/pubmed/31570575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904660116
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