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Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation
As platelets aggregate and activate at the site of vascular injury to stem bleeding, they are subjected to a myriad of biochemical and biophysical signals and cues. As clot formation ensues, platelets interact with polymerizing fibrin scaffolds, exposing platelets to a large range of mechanical micr...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210024/ https://ncbi.nlm.nih.gov/pubmed/25246564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322917111 |
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