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Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation

As platelets aggregate and activate at the site of vascular injury to stem bleeding, they are subjected to a myriad of biochemical and biophysical signals and cues. As clot formation ensues, platelets interact with polymerizing fibrin scaffolds, exposing platelets to a large range of mechanical micr...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Qiu, Yongzhi, Brown, Ashley C., Myers, David R., Sakurai, Yumiko, Mannino, Robert G., Tran, Reginald, Ahn, Byungwook, Hardy, Elaissa T., Kee, Matthew F., Kumar, Sanjay, Bao, Gang, Barker, Thomas H., Lam, Wilbur A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210024/
https://ncbi.nlm.nih.gov/pubmed/25246564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322917111
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