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Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

Cell migration plays a major role in many fundamental biological processes, such as morphogenesis, tumor metastasis, and wound healing. As they anchor and pull on their surroundings, adhering cells actively probe the stiffness of their environment. Current understanding is that traction forces exert...

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Detalhes bibliográficos
Main Authors: Trichet, Léa, Le Digabel, Jimmy, Hawkins, Rhoda J., Vedula, Sri Ram Krishna, Gupta, Mukund, Ribrault, Claire, Hersen, Pascal, Voituriez, Raphaël, Ladoux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344951/
https://ncbi.nlm.nih.gov/pubmed/22509005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117810109
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