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Substrate Topography Induces a Crossover from 2D to 3D Behavior in Fibroblast Migration

In a three-dimensional environment, cells migrate through complex topographical features. Using microstructured substrates, we investigate the role of substrate topography in cell adhesion and migration. To do so, fibroblasts are plated on chemically identical substrates composed of microfabricated...

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Detalhes bibliográficos
Main Authors: Ghibaudo, Marion, Trichet, Léa, Le Digabel, Jimmy, Richert, Alain, Hersen, Pascal, Ladoux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711370/
https://ncbi.nlm.nih.gov/pubmed/19580774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.04.024
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