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Substrate Topography Induces a Crossover from 2D to 3D Behavior in Fibroblast Migration
In a three-dimensional environment, cells migrate through complex topographical features. Using microstructured substrates, we investigate the role of substrate topography in cell adhesion and migration. To do so, fibroblasts are plated on chemically identical substrates composed of microfabricated...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711370/ https://ncbi.nlm.nih.gov/pubmed/19580774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.04.024 |
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