Substrate Topography Induces a Crossover from 2D to 3D Behavior in Fibroblast Migration

In a three-dimensional environment, cells migrate through complex topographical features. Using microstructured substrates, we investigate the role of substrate topography in cell adhesion and migration. To do so, fibroblasts are plated on chemically identical substrates composed of microfabricated...

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Bibliografiske detaljer
Main Authors: Ghibaudo, Marion, Trichet, Léa, Le Digabel, Jimmy, Richert, Alain, Hersen, Pascal, Ladoux, Benoît
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2009
Fag:
Cell Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711370/
https://ncbi.nlm.nih.gov/pubmed/19580774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.04.024
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