Actomyosin bundles serve as a tension sensor and a platform for ERK activation

Tensile forces generated by stress fibers drive signal transduction events at focal adhesions. Here, we report that stress fibers per se act as a platform for tension-induced activation of biochemical signals. The MAP kinase, ERK is activated on stress fibers in a myosin II-dependent manner. In myos...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Hirata, Hiroaki, Gupta, Mukund, Vedula, Sri Ram Krishna, Lim, Chwee Teck, Ladoux, Benoit, Sokabe, Masahiro
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Scientific Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4328752/
https://ncbi.nlm.nih.gov/pubmed/25550404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439140
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki