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Actomyosin bundles serve as a tension sensor and a platform for ERK activation
Tensile forces generated by stress fibers drive signal transduction events at focal adhesions. Here, we report that stress fibers per se act as a platform for tension-induced activation of biochemical signals. The MAP kinase, ERK is activated on stress fibers in a myosin II-dependent manner. In myos...
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| Pubblicato in: | EMBO Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4328752/ https://ncbi.nlm.nih.gov/pubmed/25550404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439140 |
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