pH dependence of melanoma cell migration: protons extruded by NHE1 dominate protons of the bulk solution

Migration and morphology of human melanoma cells (MV3) depend on extracellular pH (pH(e)) and the activity of the Na(+)/H(+) exchanger NHE1. To distinguish effects of NHE1 activity per se from effects of pH(e) we compared an NHE1-deficient mutant with rescued and wild-type cells. Time lapse video mi...

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Detalhes bibliográficos
Main Authors: Stüwe, Laura, Müller, Markus, Fabian, Anke, Waning, Judith, Mally, Sabine, Noël, Josette, Schwab, Albrecht, Stock, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230576/
https://ncbi.nlm.nih.gov/pubmed/17916606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.145185
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