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MMP3 activity rather than cortical stiffness determines NHE1-dependent invasiveness of melanoma cells
BACKGROUND: Both cell adhesion and matrix metalloproteinase (MMP) activity depend on pH at the cell surface. By regulating extracellular juxtamembrane pH, the Na(+)/H(+) exchanger NHE1 plays a significant part in human melanoma (MV3) cell migration and invasion. Because NHE1, besides its pH-regulato...
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| Publicado en: | Cancer Cell Int |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6842528/ https://ncbi.nlm.nih.gov/pubmed/31728131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1015-7 |
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