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An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

Mounting evidence suggests that the tumor microenvironment is profoundly immunosuppressive. Thus, mitigating tumor immunosuppression is crucial for inducing sustained antitumor immunity. Whereas previous studies involved intratumoral injection, we report here an inhalable nanoparticle-immunotherapy...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Yang, Crowe, William N., Wang, Lulu, Lu, Yong, Petty, W. Jeffrey, Habib, Amyn A., Zhao, Dawen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841721/
https://ncbi.nlm.nih.gov/pubmed/31704921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13094-5
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