Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection

The parasite Trypanosoma cruzi is the causative agent of Chagas disease, a potentially life-threatening infection that represents a major health problem in Latin America. Several characteristics of this protozoan contribute to the lack of an effective vaccine, among them: its silent invasion mechani...

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Bibliografiske detaljer
Udgivet i:NPJ Vaccines
Main Authors: Sanchez Alberti, Andrés, Bivona, Augusto E., Cerny, Natacha, Schulze, Kai, Weißmann, Sebastian, Ebensen, Thomas, Morales, Celina, Padilla, Angel M., Cazorla, Silvia I., Tarleton, Rick L., Guzmán, Carlos A., Malchiodi, Emilio L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604744/
https://ncbi.nlm.nih.gov/pubmed/29263868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-017-0010-z
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