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An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

Mounting evidence suggests that the tumor microenvironment is profoundly immunosuppressive. Thus, mitigating tumor immunosuppression is crucial for inducing sustained antitumor immunity. Whereas previous studies involved intratumoral injection, we report here an inhalable nanoparticle-immunotherapy...

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Foilsithe in:Nat Commun
Main Authors: Liu, Yang, Crowe, William N., Wang, Lulu, Lu, Yong, Petty, W. Jeffrey, Habib, Amyn A., Zhao, Dawen
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841721/
https://ncbi.nlm.nih.gov/pubmed/31704921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13094-5
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