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DOES AUGMENTATION OF MITOCHONDRIAL THIOREDOXIN REDUCTASE 2 IMPROVE METABOLIC FITNESS?

Mitochondrial Thioredoxin Reductase (TrxR2) is a rate limiting enzyme in the mitochondrial thioredoxin system which serves as one of the major mitochondrial ROS scavenging pathways. Txnrd2 is also a repressor of the ASK-1 oxidative stress induced apoptotic pathway. Our group previously identified a...

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Pubblicato in:Innov Aging
Autori principali: Chocron, Sandra, Pickering, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6840544/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.1462
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