Mitochondrial thioredoxin reductase 2 is elevated in long‐lived primate as well as rodent species and extends fly mean lifespan

In a survey of enzymes related to protein oxidation and cellular redox state, we found activity of the redox enzyme thioredoxin reductase (TXNRD) to be elevated in cells from long‐lived species of rodents, primates, and birds. Elevated TXNRD activity in long‐lived species reflected increases in the...

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Udgivet i:Aging Cell
Main Authors: Pickering, Andrew M., Lehr, Marcus, Gendron, Christi M., Pletcher, Scott D., Miller, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506402/
https://ncbi.nlm.nih.gov/pubmed/28474396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12596
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