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Thioredoxin reductase-1 knock down does not result in thioredoxin-1 oxidation

The active site of thioredoxin-1 (Trx1) is oxidized in cells with increased reactive oxygen species (ROS) and is reduced by thioredoxin reductase-1 (TrxR1). The purpose of the present study was to determine the extent to which the redox state of Trx1 is sensitive to changes in these opposing reactio...

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Detalhes bibliográficos
Main Authors: Watson, Walter H., Heilman, Jacqueline M., Hughes, Laura L., Spielberger, Jeanine C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387252/
https://ncbi.nlm.nih.gov/pubmed/18267104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.02.006
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