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Mice with a Deletion of Rsph1 Exhibit a Low Level of Mucociliary Clearance and Develop a Primary Ciliary Dyskinesia Phenotype

Primary ciliary dyskinesia (PCD) is a genetically and phenotypically heterogeneous disease caused by mutations in over 40 different genes. Individuals with PCD caused by mutations in RSPH1 (radial spoke head 1 homolog) have been reported to have a milder phenotype than other individuals with PCD, as...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Yin, Weining, Livraghi-Butrico, Alessandra, Sears, Patrick R., Rogers, Troy D., Burns, Kimberlie A., Grubb, Barbara R., Ostrowski, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839924/
https://ncbi.nlm.nih.gov/pubmed/30896965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0387OC
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