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Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia
Cilia play essential roles in normal human development and health; cilia dysfunction results in diseases such as primary ciliary dyskinesia (PCD). Despite their importance, the native structure of human cilia is unknown, and structural defects in the cilia of patients are often undetectable or remai...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267722/ https://ncbi.nlm.nih.gov/pubmed/25473808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6727 |
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