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Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin

Respiratory infections are a major cause of morbidity and mortality in the elderly. Previous reports have suggested that mucociliary clearance (MCC) is impaired in older individuals, but the cause is unclear. To unravel the mechanisms responsible for the age-associated decline in MCC, we investigate...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Grubb, Barbara R., Livraghi-Butrico, Alessandra, Rogers, Troy D., Yin, Weining, Button, Brian, Ostrowski, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867354/
https://ncbi.nlm.nih.gov/pubmed/26968767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00015.2016
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