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Restoring ciliary function to differentiated Primary Ciliary Dyskinesia cells with a lentiviral vector
Primary ciliary dyskinesia is a genetically heterogeneous autosomal recessive disease in which mutations disrupt ciliary function, leading to impaired mucociliary clearance and life-long lung disease. Mouse tracheal cells with a targeted deletion in the axonemal dynein intermediated chain gene Dnaic...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4124007/ https://ncbi.nlm.nih.gov/pubmed/24451115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.79 |
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