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An EM algorithm to improve the estimation of the probability of clonal relatedness of pairs of tumors in cancer patients
BACKGROUND: We previously introduced a random-effects model to analyze a set of patients, each of which has two distinct tumors. The goal is to estimate the proportion of patients for which one of the tumors is a metastasis of the other, i.e. where the tumors are clonally related. Matches of mutatio...
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| Udgivet i: | BMC Bioinformatics |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6839069/ https://ncbi.nlm.nih.gov/pubmed/31703552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3148-z |
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