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Comparison of Properties of Tests for Assessing Tumor Clonality

In a recent article Begg et al. (2007) proposed a statistical test to determine whether or not a diagnosed second primary tumor is biologically independent of the original primary tumor, by comparing patterns of allelic losses at candidate genetic loci. The proposed Concordant Mutations Test is a co...

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Main Authors: Ostrovnaya, Irina, Seshan, Venkatraman E., Begg, Colin B.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761024/
https://ncbi.nlm.nih.gov/pubmed/18266893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2008.00988.x
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